2808NRS Nursing

2808NRS Nursing

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2808NRS Nursing

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2808NRS Nursing

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Course Code: 2808NRS
University: Griffith University

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Country: Australia

Question:
For this task you need to create a single (1) slide (using PowerPoint) colour coded concept map and provide a word explanation, demonstrating analysis of the case study scenario emailed to you in week 1. A PowerPoint template file will be made available for you to customise based on your assigned case scenario.
? In your concept map you must include:1) Your Interpretation of the patient’s risk factors (from the case-study scenario) and determine how these risk factors relate to the diagnosed disease/disorder using evidence based literature;2) An outline of the links between the aetiology, cellular pathology and the pathophysiology of the diagnosed disease;3) A description of how the pathophysiology of the disease/disorder accounts for the patient’s clinical manifestations (described in the case-study scenario); and4) An analysis and interpretation including evidence-based research to suggest appropriate diagnostic assessments and treatment modalities for the patient’s diagnosis.
? In your 750 word written explanation you must:1) Explain the links between the patient’s risk factors and aetiology to account for the disease’s/disorder’s physiology.2) Describe how the disease’s/disorder’s pathophysiology manifests through the patient’s signs and symptoms (clinical manifestations).3) Justify your suggested diagnostic tests and treatment modalities listed in the concept map on their relevance and appropriateness for the diagnosed disease/disorder.
Answer:

The case study involves an 11-year-old female patient named Emilia, who has been diagnosed with autoimmune Type 1 diabetes mellitus. Emilia has a medical history of coeliac disease and tonsillectomy. Her family history included Type 1 diabetes mellitus (her father).  Emilia presented to the hospital with chief complaint of worsening of vomiting and lethargy since twenty hours. Emilia was born in Finland and has recently moved to Australia. Her Physical examination revealed weakness, deep-rapid breathing and no response to verbal commandsType 1 DM is a disorder of the immune system in which the immune system destroys its own cells in the pancreas. The disease first manifests itself in adolescence or early age. In this disease, the pancreas cannot deliver any insulin – the hormone that controls glucose levels (Chiang, Kirkman, Laffel & Peters, 2014).Insulin production is insufficient to control blood glucose levels due to the permanent destruction of beta cells in the pancreas. This destruction progresses without any apparent time until the mass of these cell reductions reaches the extent that the measurement of the insulin delivered is insufficient (Kostic et al., 2015).Pathophysiology:The slow destruction of beta-cells in the pancreas, which is inevitably due to the onset of type 1 DM, is a consequence of the immune system response (Livingstone et al., 2015). The immune system working against body’s own cells can be activated by a natural factor presented to individuals who have hereditary deficiency.Risk factors:Despite the fact that systems of etiology of Type 1 diabetes are misty, it is thought to involve following risk factors:Genetic etiology – Some ethic groups, such as Scandinavians and Sardines, are likely to have more chances of Type 1 DM.Autoantigens – Proteins that are thought to have been discarded or detected in the normal turnover of pancreatic beta cells. Activation of TH1, TH2, B lymphocytes and CD8 cells occur. Autoantigens create an uncontrolled reaction leading to beta cell destruction.Clinical manifestationsGlucose does not move in cells because insulin is not there to do it. Rather, it develops in the blood and the cells begin to starve. This leads to high glucose, which can lead to symptoms such as:Dehydration: When there is increased sugar in the blood, patient dehydrates more. This is the body’s method of removing it. A lot of water comes out with urine, which drains the body (Onengut-Gumuscu et al., 2015).Weight loss: Glucose that goes out when urinating expels calories with it. This is the reason why many people with high glucose have glucose in urea. The lack of hydration further exerts influence.Diabetic ketoacidosis (DKA): If the body can not get enough glucose for fuel, it metabolizes the fat cells. This makes synthetic compounds called ketones (Bluestone et al., 2015).Other symptoms include:Polydipsia (excessive thirst), dry mouth, unexplained weight loss (despite the fact that patient eats and feels hungry), fatigue and deep rapid breathing.DiagnosisType 1 DM, blood glucose test. Test for glucose or ketone in urea.TreatmentMany people with type 1 diabetes live long and healthy life. The way of maintaining a healthy life is to maintain glucose levels within the range given by the specialist. Emilia  needs to often undergo screening for insulin, nourishment and exercise to achieve this (Cherney et al., 2014).Emilia should be injected with insulin infusions to control glucose levels after consultation with a doctor.Changes in lifestyleExercise is a major element of the treatment of Type 1 DM. However, this does not include basic running exercise. Emilia must adjust the diet plan and dose of the insulin and the nutritional adjustment which will help in regulation of blood glucose level.
Reference list

Bluestone, J. A., Buckner, J. H., Fitch, M., Gitelman, S. E., Gupta, S., Hellerstein, M. K., … & Liu, W. (2015). Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Science translational medicine, 7(315), 315ra189-315ra189.
Cherney, D. Z., Perkins, B. A., Soleymanlou, N., Maione, M., Lai, V., Lee, A., … & von Eynatten, M. (2014). Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation, 129(5), 587-597.
Chiang, J. L., Kirkman, M. S., Laffel, L. M., & Peters, A. L. (2014). Type 1 diabetes through the life span: a position statement of the American Diabetes Association. Diabetes care, 37(7), 2034-2054.
Kostic, A. D., Gevers, D., Siljander, H., Vatanen, T., Hyötyläinen, T., Hämäläinen, A. M., … & Lähdesmäki, H. (2015). The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes. Cell host & microbe, 17(2), 260-273.
Livingstone, S. J., Levin, D., Looker, H. C., Lindsay, R. S., Wild, S. H., Joss, N., … & McKnight, J. A. (2015). Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010. Jama, 313(1), 37-44.
Onengut-Gumuscu, S., Chen, W. M., Burren, O., Cooper, N. J., Quinlan, A. R., Mychaleckyj, J. C., … & Achuthan, P. (2015). Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nature genetics, 47(4), 381.

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2808NRS Nursing

2808NRS Nursing

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2808NRS Nursing

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2808NRS Nursing

0 Download5 Pages / 1,088 Words

Course Code: 2808NRS
University: Griffith University

MyAssignmentHelp.com is not sponsored or endorsed by this college or university

Country: Australia

Question:
For this task you need to create a single (1) slide (using PowerPoint) colour coded concept map and provide a 750 word explanation, demonstrating analysis of the case study scenario emailed to you in week 1. A PowerPoint template file will be made available for you to customise based on your assigned case scenario.
 
In your concept map you must include:1) Your Interpretation of the patient’s risk factors (from the case-study scenario) and determine how these risk factors relate to the diagnosed disease/disorder using evidence based literature;2) An outline of the links between the aetiology, cellular pathology and the pathophysiology of the diagnosed disease;3) A description of how the pathophysiology of the disease/disorder accounts for the patient’s clinical manifestations (described in the case-study scenario); and4) An analysis and interpretation including evidence-based research to suggest appropriate diagnostic assessments and treatment modalities for the patient’s diagnosis.
In your 750 word written explanation you must:1) Explain the links between the patient’s risk factors and aetiology to account for the disease’s/disorder’s pathophysiology.2) Describe how the disease’s/disorder’s pathophysiology manifests through the patient’s signs and symptoms (clinical manifestations).3) Justify your suggested diagnostic tests and treatment modalities listed in the concept map on their relevance and appropriateness for the diagnosed disease/disorder.
Answer:

From the case study of Emilia, it is evident that family history of type 1 diabetes (T1D), celiac disease and tonsillectomy are the risk factors that accounted for her condition. T1D has an inherited susceptibility and if any of the parents has the disease, the likelihood increases of their child in developing the disorder. Research has stated that if father is having T1D, the risk of developing the condition is slightly higher than if any sibling or mother having the disease (Atkinson, 2012).
Moreover, the risk of T1D development increases by certain variants of HLA like HLA-DQB1, HLA-DQA1 and HLA-DRB1 genes that provide instructions for protein synthesis playing a critical role in the functioning of immune system considering it an autoimmune disorder. At the age of seven, Emilia was diagnosed with celiac disease and this also increases the development of T1D condition. According to a study conducted by Elfström, Sundström and Ludvigsson, (2014) celiac disease is strongly associated with significant increased risk of subsequent T1D in children under 20 years.
It has been well-established that children with celiac disease are at high risk for T1D within 5 years after first celiac disease diagnosis (Smyth et al., 2008). This is evident in the case study where Emilia was diagnosed with celiac disease at the age of 7 years and within 5 years, at the age of 11 years, she was diagnosed with T1D. HLA-DQ2 is a risk factor that positively increases the risk of T1D expressing tissue transglutaminase auto-antibodies in celiac disease.
Therefore, there is increased risk of T1D in celiac disease patients attributable to HLA characteristics. Tonsillectomy procedure affects the functioning of immune system that increases the risk of T1D among children. An autoimmune reaction where the immune system attacks its own body cells may be activated and destroy the beta cells in pancreases interfering with inclusion production (Atkinson, Eisenbarth & Michels, 2014). Although, there is little evidence on risk of T1D in children after tonsillectomy, however, surgical removal of tonsils affect the normal functioning and early development of immune system making children prone to long-term risks and autoimmune diseases like T1D (Bluestone, Herold & Eisenbarth, 2010).
Answer two
The first signs of T1D when insulin is not being produced in the body with elevated blood glucose levels, the rapid symptoms that are observed are extreme thirst, increased urination, vomiting and extreme tiredness. These signs and symptoms are also witnessed in Emilia as a result of manifestation of T1D. Excessive thirst (polydipsia) and frequent urination (polyuria) are the classic T1D symptoms that occur when excess glucose builds up in the body as seen in Emilia. During this time, kidneys are unable to filter and absorb the excess glucose that results in excretion through urine triggering increased urination, dehydration and increased thirst (Cooke & Plotnick, 2008).
She was lethargic due to dehydration, increased urination and inability of body to function properly and utilize glucose for energy needs. Vomiting occurs when the blood glucose levels tend to rise and makes the body prone to ketone body production. Ketones are acids and its increased levels leads to Diabetic ketoacidosis (DKA) resulting in vomiting and deep rapid breathing as witnessed in Emilia. DKA is common in T1D, when advanced enough leads to unconsciousness and due to this reason; Emilia was unresponsive towards verbal commands resulting from a combination of severely elevated blood glucose levels, shock, dehydration and exhaustion (American Diabetes Association, 2015).
Answer three
For the diagnosis of T1D, Glycated hemoglobin (A1C) test is performed that indicates average blood glucose level in last three months and measures the blood sugar percentage attached to haemoglobin (Gallagher, Le Roith & Bloomgarden, 2009). Higher the levels, more haemoglobin attached where 6.5% or higher indicates T1D. C-peptide testing can also be done as peptide levels matches with insulin levels indicating its production in the body and low levels of insulin and C-peptide points to T1D. Glutamic Acid Decarboxylase Autoantibodies (GADA or Anti-GAD) test detects antibodies that are against specific enzymes in beta cells of pancreas producing insulin (Bingley, 2010).
TD can be managed through right amount of insulin administration while working closely with the medical team. This can be delivered through pens or syringes or pumps. The type and frequency of insulin dosage vary on a daily basis and may be required multiple times in a day. Daily blood sugar monitoring is important for Emilia as it helps to estimate carbohydrate intake for lowering blood sugar levels. A balanced diet and physical exercise is important for her ensuring appropriate nutritional intake and healthy weight maintenance curbing the effects of diabetic wear on her body. Regular medical check-ups and meeting with diabetic care team is also important in managing Emilia’s T1D condition and in avoiding its effects on her body (Chiang, Kirkman, Laffel & Peters, 2014).
Reference list
American Diabetes Association. (2015). Standards of medical care in diabetes—2015 abridged for primary care providers. Clinical   diabetes: a publication of the American Diabetes Association, 33(2), 97. DOI: 10.2337/diaclin.33.2.97
Atkinson, M. A. (2012). The pathogenesis and natural history of type 1 diabetes. Cold Spring Harbor perspectives in medicine, 2(11),   a007641. Doi: 10.1101/cshperspect.a007641
Atkinson, M. A., Eisenbarth, G. S., & Michels, A. W. (2014). Type 1 diabetes. The Lancet, 383(9911), 69-82. Doi:   
Bingley, P. J. (2010). Clinical applications of diabetes antibody testing. The Journal of Clinical Endocrinology & Metabolism, 95(1), 25-  33. Doi:
Bluestone, J. A., Herold, K., & Eisenbarth, G. (2010). Genetics, pathogenesis and clinical interventions in type 1   diabetes. Nature, 464(7293), 1293. Doi:
 Chiang, J. L., Kirkman, M. S., Laffel, L. M., & Peters, A. L. (2014). Type 1 diabetes through the life span: a position statement of the   American Diabetes Association. Diabetes care, 37(7), 2034-2054. Doi: 
Cooke, D. W., & Plotnick, L. (2008). Type 1 diabetes mellitus in pediatrics. Pediatr Rev, 29(11), 374-84. DOI: 10.1542/pir.29-11-374
Elfström, P., Sundström, J., & Ludvigsson, J. F. (2014). Systematic review with meta?analysis: associations between coeliac disease and   type 1 diabetes. Alimentary pharmacology & therapeutics, 40(10), 1123-1132. Doi: 
Gallagher, E. J., Le Roith, D., & Bloomgarden, Z. (2009). Review of hemoglobin A1c in the management of diabetes. Journal of   diabetes, 1(1), 9-17. Doi:
 Smyth, D. J., Plagnol, V., Walker, N. M., Cooper, J. D., Downes, K., Yang, J. H., … & Heap, G. A. (2008). Shared and distinct genetic   variants in type 1 diabetes and celiac disease. New England Journal of Medicine, 359(26), 2767-2777. Doi:   10.1056/NEJMoa0807917

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5N1794 Safety And Health At Work
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13

Course Code: 5N1794
University: University College Cork

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Answer:
Assignment 1
Answer to question 1
I have conducted a survey at my workplace maned Lady’s Hospice and Care Services to observe the working environment. The aim of the survey is to find if it is a safe, healthy, secured and fulfilling place to work. A visual survey was conducted to locate and record the safety signs in the workplace. The objective of the survey is to observe and list different types of signs, location, their prom…
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Tags:
Australia Maple Ridge Management Introduction to film studies University of New South Wales Masters in Business Administration 

400837 Health And Socio Political Issues In Aged Care
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0 | Pages :
14

Course Code: 400837
University: Western Sydney University

MyAssignmentHelp.com is not sponsored or endorsed by this college or university

Country: Australia

Answers:
Introduction
Palliative care services are designed to improve the life of patient with progressive disease. People receiving palliative care have illness that has no prospect of cure.  As per the World Health Organisation, palliative care is a care given to patient suffering from life threatening illness to improve their quality of life by preventing and providing relief from sufferings by early recognition , assessment and trea…
Read
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Tags:
Australia Minchinbury Management University of New South Wales 

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0 | Pages :
8

Course Code: PUBH6304
University: The University Of Newcastle

MyAssignmentHelp.com is not sponsored or endorsed by this college or university

Country: Australia

Answers:
Human Immunodeficiency Virus Infection and Acquired Immune Deficiency Syndrome (HIV/AIDS) is the spectrum of medical conditions caused due to human immunodeficiency virus (HIV) following which the patient suffers from a series medical complications due to suppression of the immune system of the body. With the progression of the disease, the patient is likely to suffer from a wide range of infections like tuberculosis and other opportu…
Read
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Tags:
United States Newark Management University of New York Masters in Business Administration 

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0 | Pages :
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Course Code: CON321
University: University Of Southern Maine

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Answer:
Introduction
Leadership in the hospital is the ability to influence the staff toward providing quality health care. Leadership involves influencing human behavior to create a positive working environment (Langlois, 2012). Good leadership enables healthy relationships among staffs in the hospital enhancing quality delivery of health care services. Leadership is responsible to building teams that have trust, respect, support and effecti…
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BL9412 Public Health
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35

Course Code: BL9412
University: University Of The West Of England

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Country: United Kingdom

Answer:
Introduction
According to the researchers, it can be said that the management of the health care organizations has become a difficult task nowadays and the reason behind this is the occurrence of various issues in this sector (Hall et al., 2014). Therefore, the administrative employees of the organization should incorporate various revolutionized strategies for enriching the worth of care provided by the hospital to its clients and re…
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Tags:
Australia Ryde Management Information system strategy University of New South Wales (UNSW) Masters in Business Administration 

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